Symmetry Analysis in Mechanistic Studies of Nucleophilic Substitution and β-Elimination Reactions
نویسندگان
چکیده
منابع مشابه
Symmetry Analysis in Mechanistic Studies of Nucleophilic Substitution and β-Elimination Reactions
A mechanistic study of the bimolecular nucleophilic substitution (SN2) reaction for halomethane CH3X (X = Cl, Br, or I) is approached by using symmetry principles and molecular orbital theory. The electrophilicity of the functionalized sp–carbon is attributable to a 2p-orbital-based antibonding MO along the C–X bond. This antibonding MO, upon accepting an electron pair from a nucleophile, gives...
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What does the term "nucleophilic substitution" imply? • A nucleophile is an the electron rich species that will react with an electron poor species • A substitution implies that one group replaces another. Nucleophilic substitution reactions occur when an electron rich species, the nucleophile, reacts at an electrophilic saturated C atom attached to an electronegative group (important), the lea...
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ژورنال
عنوان ژورنال: Symmetry
سال: 2010
ISSN: 2073-8994
DOI: 10.3390/sym2010201